In 2005, she explained she had intended to reinvent herself, using the given name of Portia, a character from William Shakespeare's The Merchant of Venice, and an Italian last name.
She was educated at Melbourne Girls Grammar School and the University of Melbourne, where she studied law.
She and De Generes became engaged when De Generes proposed in 2008.
In 2010, de Rossi published her autobiography, titled Unbearable Lightness: A Story of Loss and Gain, within which she wrote about the turmoil that she had experienced in her life, including suffering from anorexia nervosa and bulimia and being misdiagnosed with lupus.
American comedian Ellen De Generes is famous for her humor sense but like other humans, she also has her serious and sad side.
I will miss playing Elizabeth North but I've made the decision to focus on a business opportunity. " Creator Shonda Rhimes added, "I have been a fan of Portia's for years and it was an honor to have her join our Scandal family." In May 2018, de Rossi announced on The Ellen De Generes Show that she would be retiring from acting, though she later elaborated that she would make an exception for future seasons of Arrested Development.
In May of 2007, she was featured as one of 100 Most Beautiful in a People special edition.
TV Guide included her and Ellen De Generes in their Power A-List couples in 2007.
This fourth season consisted of 15 new episodes, which debuted at the same time on Netflix on .
Each episode focused on one particular character, with de Rossi's Lindsay featured in Episode 3, "Indian Takers," and Episode 8, "Red Hairing," and also appearing in several other episodes of the season.